Assume this hypothetical situation: an American pharmaceutical company, Maxwell Fisch Pharmaceuticals, Inc., wishes to perform clinical trials involving a new antipsychotic medication, Klezac. Klezac is in its third phase of the clinical stage of the drug research process. Once the testing is complete, Maxwell plans to submit a New Drug Application, the official request to begin marketing Klezac, to the Food and Drug Administration. The new drug is expected to receive FDA approval in 2 or more years. The company decides (...) to shift its research and development activities to Z, a small, developing country. In doing so, Maxwell is following the course taken by numerous other drug companies who wish to take advantage of faster governmental approval in foreign sites and ensuing cheaper research costs. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Cocceius and the Jewish CommentatorsAdina M. YoffieThe case of Johannes Cocceius defies the commonplace that Leiden University (and perhaps post-Reformation, confessionalized Europe in general) turned away from humanist scholarship in the first quarter of the seventeenth century. In 1650 Cocceius (1603-69), a Bremen-born Oriental philology professor at Franeker, joined the Leiden theological faculty and wrote a treatise, Protheoria de ratione interpretandi sive introductio in philologiam sacram (De ratione). He (...) praised such rabbinic exegetes as Rashi (1040-1105) and David Kimchi (ca. 1160-ca. 1235) in humanist terms for their erudition. At the same time the "new" Cartesian philosophy was taking hold in the arts faculty, and mathematics instruction was encroaching on scholastic formal logic.1 Leiden would become famous for Cartesianism, mathematics, and "Calvinist Copernicanism" in the second half of the seventeenth century, but Cocceius still worked in the tradition of advanced humanist scholarship that had made the institution famous in the sixteenth century.2Leiden's earlier reputation was due in large part to the biblical humanist work of such Renaissance polymaths as Joseph Justus Scaliger (1540-1609) and Hugo Grotius (1583-1645), but by Cocceius's time Leiden theologians were subject to greater Church and State control. As Jonathan Israel and Edwin Rabbie have shown, in response to the controversy that surrounded Jacobus Arminius and his stand on predestination, the Synod of Dordrecht (Dort) drafted an anti-Arminian statement in 1619; any professor who did not sign was subject [End Page 383] to exile from the republic in addition to dismissal from his post.3 Innovative theology, exegesis, and philology suffered as professors, fearing State and Church reprisals, turned to "dogmatic humanism." As Henk Jan de Jonge has explained, this meant that "almost all the theologians of seventeenth-century Leiden who concerned themselves with the explanation of the New Testament placed exegesis at the service of dogmatic objectives."4 Unlike his fellow Leiden theologians, Cocceius pursued biblical humanism and Christian Hebraism through the study of Hebrew, Greek, and Aramaic-and he did so in a unique way. He was not the first to use Jewish commentaries and even Jewish post-biblical literature for the purpose of reconstructing the original Hebrew Bible, but he was innovative in praising rabbinic scholars as fellow humanists and in incorporating their scholarship into his Christological exegesis and philosophy. He did so, furthermore, not as an independent scholar or pastor or even as a professor of Hebrew; but as the holder of a university chair in theology at a confessionalized university in a century hostile to his brand of late humanism.Although he came to Leiden as a theologian, Cocceius had impressive training as an Orientalist. He had studied with the famous scholar Sixtinus Amama (1593-1629) and polished his Hebrew and Aramaic by working with a Jewish tutor from Hamburg.5 While still a student at Franeker, Cocceius wrote a translation and commentary of the Talmudic tractate Sanhedrin. A few years later he began composing commentaries on the Pentateuch, and, by the time he arrived at Leiden, he had completed one lecture, series of lectures, or piece of writing on every book of the Old Testament. These commentaries were based not only on Cocceius's extensive knowledge of Oriental languages but also on his readings of medieval Jewish commentators. These were the same commentators that Cocceius would later praise in chapter eight of the De ratione.These humanist achievements were much at variance with Cocceius's public persona as perhaps the most prominent Dutch Calvinist theologian of the seventeenth century. For approximately 100 years after his death in 1669 a faction of Leiden theologians calling themselves "Cocceians" battled the "Voetians," followers of Gisbertus Voetius, for the soul of the Dutch Church.6 At Leiden he lectured on the Pauline Epistles, a typical subject for a seventeenth-century Calvinist theologian, and he worked on his famous theological tract, the salvation-historical Summa doctrinae de foedere et testamento Dei (1648). Neither the De ratione nor his voluminous biblical commentary (except [End Page 384] for a short treatise on the last six chapters of Deuteronomy) was published in Cocceius's lifetime. His son Johann Heinrich released these and his father's... (shrink)

The Blackwell Companion and Blackwell Guide to the philosophy of education, edited respectively by Randall Curren and by Nigel Blake, Paul Smeyers, Richard Smith and Paul Standish, are potentially field-defining volumes. The present essay moves back and forth between the two books to assess the overall impression they provide of the ‘state of the art’. Whilst both texts can be criticised for failing to engage sufficiently with non-philosophical work on education, these are otherwise estimable volumes, containing many fine essays that (...) can be read with profit. (shrink)

The Blackwell Companion and Blackwell Guide to the philosophy of education, edited respectively by Randall Curren and by Nigel Blake, Paul Smeyers, Richard Smith and Paul Standish, are potentially field-defining volumes. The present essay moves back and forth between the two books to assess the overall impression they provide of the ‘state of the art’. Whilst both texts can be criticised for failing to engage sufficiently with non-philosophical work on education, these are otherwise estimable volumes, containing many fine essays that (...) can be read with profit. (shrink)

Patient centred diagnosis is best practised through shared decision making; an iterative dialogue between doctor and patient, whichrespects a patient’s needs, values, preferences, and circumstances. -/- Shared decision making for diagnostic situations differs fundamentally from that for treatment decisions. This has important implications when considering its practical application. -/- The nature of dialogue should be tailored to the specific diagnostic decision; scenarios with higher stakes or uncertainty usually require more detailed conversations.

Ethics, Policy & Environment, Volume 14, Issue 2, Page 231-237, June 2011.

Dan ZAHAVI, Husserl and Transcendental Intersubjectivity. A Response to the Linguistic-Pragmatic Critique ; Françoise DASTUR, Chair et langage. Essais sur Merleau-Ponty ; Jean GREISCH, Michel Henry et l’épreuve de la vie ; Elisabeth STRÖKER, The Husserlian Foundations of Science ; John McCUMBER, Metaphysics and Oppression, Heidegger’s Challenge to Western Philosophy ; Marc RICHIR, Phénoménologie en esquisses. Nouvelles fondations ; Raphaël GÉLY, La genèse du sentir. Essai sur Merleau-Ponty ; John SALLIS, Force of Imagination: The Sense of the Elemental ; Bin (...) KIMURA, L’entre. Une approche phénoménologique de la schizophrénie ; Dermot MORAN, Tim MOONEY, The Phenomenology Reader ; Ion COPOERU, Structuri ale constituirii ; Fabio CIARAMELLI, La distruzione del’desiderio. Il narcisismo nell’epoca di consumo di massa ; Pierre KELLER, Husserl and Heidegger on Human Experience. (shrink)

This paper examines people's reasoning about identity continuity and its relation to previous research on how people value one-of-a-kind artifacts, such as artwork. We propose that judgments about the continuity of artworks are related to judgments about the continuity of individual persons because art objects are seen as physical extensions of their creators. We report a reanalysis of previous data and the results of two new empirical studies that test this hypothesis. The first study demonstrates that the mere categorization of (...) an object as “art” versus “a tool” changes people's intuitions about the persistence of those objects over time. In a second study, we examine some conditions that may lead artworks to be thought of as different from other artifacts. These observations inform both current understanding of what makes some objects one-of-a-kind as well as broader questions regarding how people intuitively think about the persistence of human agents. (shrink)

Bioethics, Volume 36, Issue 3, Page 267-273, March 2022.

Informal logic has expanded the concept of an 'argument' beyond that presented traditionally by formal logicians-to include arguments as encountered in 'real-life'. Existent definitions of argument structure are argued to be inadequate by failing to fully recognise that, ultimately, arguments have a human source. Accordingly, a new definition is proposed which appeals to relevant cognitive and behavioural factors. The definition retains some traditional concepts, but introduces the term 'supportive' as a modification to 'premiss'. The concept of a 'persuader' is also (...) developed. The definition is argued to capture more fully the intricacies, subtleties and rich diversity of informal arguments. (shrink)

This paper argues that professionals who make boundary-related decisions should be guided by relationship-based practice. In our roles as service users and professionals, drawing from our lived experiences of professional relationships, we argue we need to move away from distance-based practice. This includes understanding the boundary stories and narratives that exist for all of us – including the people we support, other professionals, as well as the organisations and systems within which we work. When we are dealing with professional boundary (...) issues, we should centre relationship-building skills that are central to many other aspects of our work. Skills that foster relationships at all levels – between professionals, service users, and services – need to be revalued. Our final recommendation is to create, develop, and foster safer spaces within and outside of organisations, as well as inter-professionally, for the discussion and exploration of boundary-related issues and practice. We are interested in hearing from those with experiences of being marginalised by boundaries so that they can inform a reshaping of our collective ideas around boundary related practices. To foster relationship-based practices in organisations, we have outlined several recommendations here; however, we recognize that these do not go far enough, and that collective action is needed to inform systemic change. (shrink)

This article suggests a way to circumvent some of the problems that follow from the lack of consensus on a definition of emotion (Izard, 2010; Kleinginna & Kleinginna, 1981) and emotion regulation (Cole, Martin, & Dennis, 2004) by adopting a conceptual framework based on discrete emotions theory and focusing on specific emotions. Discrete emotions theories assume that neural, affective, and cognitive processes differ across specific emotions and that each emotion has particular motivational and regulatory functions. Thus, efforts at regulation should (...) target the specific dysregulated emotions. The positive effects of emotion regulation are more likely to be optimized when they result from or lead to emotion utilization—the constructive use of the energy of emotion arousal. Effective processes for regulation differ for basic emotions and emotion schemas. This article identifies neural systems that facilitate emotion experiences and emotion regulation processes. It considers the implications of the developmental change from basic emotions to emotion schemas, and also briefly discusses the effects of interventions on changes in emotion knowledge, emotion regulation, and social and emotional competence. (shrink)

This article offers a series of critical theorizations on the biopolitical dimensions of methicillin-resistant Staphylococcus aureus (MRSA), with specific attention to what has recently been referred to in the United States as the ‘MRSA Epidemic’. In particular, we reflect on the proliferation of biomedical discourses around the ‘spread’, and the pathogenic potentialities, of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). We turn to the work of Roberto Esposito and Jean-Luc Nancy to better make sense of how, during this immunological crisis, the individualized (...) fleshy and fluid body is articulated to dimensions of community and corporeal proximity; the body is thus conceived in popular biopolitical framings as a site of transmission, inoculation, and isolation – as a living ecological and pathological vessel. We give emphasis to the spatial relations of flesh, namely in how biomedical ‘experts’ have sought to (bio-)technologize spaces of heightened communal bodily contact (such as playgrounds or gymnasia). (shrink)

We thank Parker and Wright for engaging in this roundtable debate in such a spirited way. The ‘Pharmacogenetic [test] to Avoid Loss of Hearing’ Trial is the first time a genetic point of care test has been applied in the acute neonatal setting; therefore, it is not surprising that questions have been raised which require debate, discussion and clarification. Parker and Wright misattribute several assumptions to the roundtable authors, which we would like to clarify here. Since they raise wider questions (...) about the PALOH trial itself, several of the roundtable discussants have made a joint response. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

The employment application form is a major source of information about candidates for many companies. It is also a potential source of infringement by the company upon the privacy of the individual. Although September 1984 saw the passing into law of the Data Protection Act, the U.K. has not been in the forefront of civil rights where employees and personal information are concerned. During an extended interview with members of a personnel department of a major company, several issues relating to (...) privacy issues were revealed and these are discussed in the paper. Although these interviews were carried out before the new law came into effect, they do show that this and many similar organisations may experience problems over compliance. This is particularly likely in the computerisation of personnel records and employees' access to their personal information. (shrink)

The proliferation of personal data collection practices fundamentally reshapes how society is ordered and commercialized, and demands reconsideration of the possibilities for a just and equitable s...

Throughout his life, John Tyler Bonner contributed to major transformations in the fields of developmental and evolutionary biology. He pondered the evolution of complexity and the significance of randomness in evolution, and was instrumental in the formation of evolutionary developmental biology. His contributions were vast, ranging from highly technical scientific articles to numerous books written for a broad audience. This historical vignette gathers reflections by several prominent researchers on the greatness of John Bonner and the implications of his work.